| Institution: | 1. Department of Chemistry, Faculty of Basic Sciences, Hakim Sabzevari University, Sabzevar, 96179-76487 Iran;2. University of Rostock, Leibniz Institute for Catalysis, Albert-Einstein-Straße 29a, 18059 Rostock, Germany
University of Rostock, Institute of Chemistry, Physical and Theoretical Chemistry, Albert-Einstein-Straße 21, 18059 Rostock, Germany |
| Abstract: | In this study, we have investigated delivery of cisplatin as the anticancer drug molecules in different carbon nanotubes (CNTs) in the gas phase using molecular dynamics simulation. We examined the shape and composition of the releasing agent by using the different nanowires and nanoclusters. We also investigated the doping effect on the drug delivery process using N-, Si, B-, and Fe-doped CNTs. Different thermodynamics, structural, and dynamical properties have been studied by using the pure and different doped CNTs in this study. Our results show that the doping of the CNT has significant effect on the rate of the drug releasing process regardless of the composition of the releasing agent. © 2019 Wiley Periodicals, Inc. |
