星形聚乳酸

星形聚乳酸以其独特的结构与性能引起了人们的广泛兴趣，通常使用“先核后臂”法进行合成。本文根据不同类型的“核”进行分类，如小分子多羟基醇（天然糖醇）、无机（杂环）化合物的衍生物、金属有机化合物、多元酚的衍生物和星形高分子等，综述了星形聚乳酸近年来合成（尤其是丙交酯开环聚合法合成）、性能与应用等方面的研究进展，指出星形聚乳酸高分子量、低黏度、良好溶解性和热稳定性等优点有利于其在药物缓释等生物医用材料中的加工应用。

Star-shaped Polylactic Acid

The star-shaped polylactic acid (SPLA) have received considerable attention due to their unique structure and good properties. Usually, SPLA are synthesized by the “core first” method., which classified by different “core” in SPLA, such as small molecular polyol (including natural sugar alcohols), hydroxyl-terminated (cyclotri)phosphazene derivatives, hydroxyl-terminated metallic organic compounds, hydroxyl-terminated phenolic derivatives, and some star-shaped macroinitiator. The progress on their synthesis, especially via the ring-opening polymerization of lactide, properties and application are summarized. It is pointed out that the higher mulecular weight and lower viscosity, better solubility and thermal properties made SPLA have more application in biomedical material (including drug delivery carrier) than linear polylactic acid (LPLA).