Exonuclease-assisted cascaded recycling amplification for label-free detection of DNA |
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| Authors: | Bi Sai Li Li Cui Yangyang |
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| Affiliation: | State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China. bisai11@126.com |
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| Abstract: | ![]()
The network consisting of three kinds of unlabeled stem-loop DNA molecular beacons (MBs) is activated by target DNA in the presence of exonuclease-III (Exo-III), achieving the concept of exonuclease-assisted cascaded recycling amplification (Exo-CRA) for DNA detection with a wide dynamic range of 8 orders of magnitude. |
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