Regioselective Nitration of Phenols by NaNO3 in Microemulsion |
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| Authors: | Jian-Zhong Jiang Li-Ting Lu Zheng-Yong Liang Zheng-Gang Cui |
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| Institution: | 1. School of Chemical and Material Engineering, Jiangnan University , Wuxi, Jiangsu, P. R. China J.Z.Jiang@hotmail;3. School of Chemical and Material Engineering, Jiangnan University , Wuxi, Jiangsu, P. R. China;4. College of Chemical Engineering, Zhengzhou University , Zhengzhou, P. R. China |
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| Abstract: | Highly regiospecific mononitration of phenols and substituted phenols was carried out in TX100-based microemulsion. The use of inexpensive and relatively nontoxic acidic reagent is an advantage of this method. The effect of various parameters such as concentration of NaNO3, temperature, and agitation speed on reaction system have been investigated. Exclusive ortho-selectivity was observed for all the phenols subjected to this protocol. |
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| Keywords: | Hydrochloric acid microemulsion mononitration phenols |
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