Abstract: | Samples presented for chemical analysis are invariably mixtures, often very complex mixtures. This has led to the widespread acceptance and application of what have become called hyphenated chromatographic techniques. These techniques are combinations of chromatographic instrumentation with some (usually) spectroscopic technique. In this review, we treat the most important and useful of these combinations. The basic instrumental features of each method are described, and possible applications are discussed. The relative capabilities of each technique are weighed, and tradeoffs are discussed. In closing, a list of suggested further reading is provided. |