Die Konstitution von Roridin D. Verrucarine und Roridine, 12. Mitteilung

The antibiotic roridin D (C₂₉H₃₈O₉), a companion of roridin A, yields on base catalysed hydrolysis verrucarol ( 3 ) and the hitherto unknown 2, 3-epoxy-2-anhydrororidinic acid ( 4 ) (C₁₄H₁₈O₇). Roridin D is a macrocyclic diester to which structure 1 is assigned. In roridin D an epoxy group replaces the hydroxyl group of roridin A.