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Antibiotics produced at the G. F. Gauze Scientific-Research Institute of New Antibiotics,Russian Academy of Medical Sciences (marking the Fiftieth Anniversary of the Institute). (Review)
Authors:E N Olsufyeva  M N Preobrazhenskaya
Institution:(1) G. F. Gauze Scientific-Research Institute of New Antibiotics, Russian Academy of Medical Sciences, Moscow, Russia
Abstract:The major achievements of the G. F. Gauze Scientific-Research Institute of New Antibiotics, Russian Academy of Medical Sciences, over the last 50 years are reviewed. The structures of antibiotics and related compounds discovered at the Institute and important for medical practise and/or of theoretical interest as new compounds with high biological activity are described.Dedicated to the memory of Director of the G. F. Gauze Scientific-Research Institute of New Antibiotics, Russian Academy of Medical Sciences, and Corresponding Member of the Russian Academy of Medical Sciences Prof. Yu. V. Dudnik (1938–2003).Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1603–1618, November, 2004.
Keywords:antibiotics  oxygen-containing heterocyclic antibiotics  nitrogen-containing heterocyclic antibiotics  sulfur-containing heterocyclic antibiotics  macrocyclic peptides  antibacterial activity  antiproliferative activity  antiviral activity  hypolipidemic activity  chemical modification
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