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An alternative quinoline synthesis by via Friedländer reaction catalyzed by Yb(OTf)3 |
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| Authors: | Salvatore GenoveseFrancesco Epifano Maria Carla MarcotullioCaroline Pelucchini Massimo Curini |
| Affiliation: | a Dipartimento di Scienze del Farmaco, Università ‘G. D’Annunzio’ di Chieti-Pescara, Via dei Vestini 31, 66100 Chieti Scalo (CH), Italy b Dipartimento di Chimica e Tecnologia del Farmaco, Sezione di Chimica Organica, Università degli Studi di Perugia, Via del Liceo 1, 06123 Perugia, Italy |
| Abstract: | Quinolines have been synthesized in very good yields from 2-aminoarylketones and differently substituted carbonyl compounds in the presence of Yb(OTf)3 as the catalyst. The method is applicable to both cyclic and acyclic carbonyl compounds with only slight differences in the experimental procedure. |
| Keywords: | Quinolines 2-Aminobenzophenone Acetylacetone Yb(OTf)3 |
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