Synthesis of 6-chloroquinolines using benzyltrimethylammonium tetrachloroiodate as a selective chlorinating agent and an efficient generator of HCl |
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| Authors: | Liqiang Wu Chunguang Yang Binxuan Niu and Fulin Yan |
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| Institution: | (1) School of Pharmacy, Xinxiang Medical University, 453003 Xinxiang, Henan, People’s Republic of China |
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| Abstract: | Abstract A simple and efficient one-pot synthesis of 6-chloroquinolines was achieved in good yields via the three-component reaction
of 2-aminoaryl ketones, α-methylene carbonyl compounds, and BTMA ICl4 in AcOH. |
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