Three-component reactions of isocyanides, dialkyl acetylenedicarboxylates, and trans-cinnamoyl chlorides for the synthesis of highly functionalized 2-vinyl furans |
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| Authors: | Abbas Ali Esmaeili Mahdieh Zangouei Rahele Hosseinabadi Ali Reza Fakhari |
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| Institution: | (1) Chemistry Department, University of Birjand, Birjand, Iran;(2) Department of Chemistry, Ferdowsi University of Mashhad, Mashhad, Iran;(3) Department of Chemistry, Faculty of Sciences, Shahid Beheshti University, G. C., P.O. Box 19396-4716, Evin, Tehran, Iran |
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| Abstract: | Abstract In this study, we present a convenient and efficient method for the synthesis of novel, highly substituted 2-vinyl furans
using a three-component reaction. The zwitterions generated from the reaction of isocyanides and dialkyl acetylenedicarboxylates
are reacted with trans-cinnamoyl chlorides to produce the desired products in good yields. |
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