Clauson–Kaas-Type Synthesis of Pyrrolyl-phenols,from the Hydrochlorides of Aminophenols,in the Presence of Nicotinamide |
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| Authors: | Maria Chatzopoulou Eleni Kotsampasakou |
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| Institution: | Department of Pharmaceutical Chemistry, School of Pharmacy , Aristotle University of Thessaloniki , Thessaloniki , Greece |
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| Abstract: | A facile Clauson–Kaas-type pyrrolyl-phenol synthesis has been achieved in the presence of nicotinamide, which is inexpensive and nontoxic. The starting material is aminophenol hydrochloride. This is advantageous in certain cases because it is the only isolatable form of the corresponding aminophenol. Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications® for the following free supplemental resource: Full experimental and spectral details.] |
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| Keywords: | Aminophenol hydrochloride Clauson–Kaas nicotinamide pyrrolyl-phenol |
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