Facile and Convenient Synthesis of Pyrazole,Pyridine, Pyridazine,Pyrazolo[3,4-b]pyridine,and Pyrazolo[5,1-c][1,2,4]triazine Derivatives |
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| Authors: | Nabila A Kheder Yahia N Mabkhot |
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| Institution: | 1. Department of Chemistry, Faculty of Science, Cairo University , Giza, Egypt;2. Department of Chemistry, Faculty of Science, Zamar University , Zamar, Yemen |
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| Abstract: | Abstract A convenient synthesis of a series of pyrazole, pyridine, pyridinethione, pyridazine, pyrazolo3,4-b]pyridine, imidazo1,2-a]pyrimidine, and pyrazolo5,1-c]1
Kumar , R. 5-(1-Substituted)alkyl pyrimidine nucleosides as antiviral (herpes) agents . Curr. Med. Chem. 2004 , 11 , 2749 – 2766 . Google Scholar] 2
Holy , A. ;
Günter , J. ;
Dvoráková , H. ;
Masojídková , M. ;
Andrei , G. ;
Snoeck , R. ;
Balzarini , J. ;
De Clercq , E. Structure–antiviral activity relationship in the series of pyrimidine and purine N-2-(2-phosphonomethoxy)ethyl] nucleotide analogues, 1: Derivatives substituted at the carbon atoms of the base . J. Med. Chem. 1999 , 42 , 2064 – 2086 . Google Scholar] 4
Brandes , W. ;
Daum , W. ;
Krauss , P. Fungicidal oxime ethers. Ger. Patent 2,623,847, 1977; Chem. Abstr . 1978 , 88 , 120822h . Google Scholar]]triazine derivatives incorporating a pyrimidine moiety, via the reactions of the versatile, readily accessible 3-oxo-N-(pyrimid-2-yl)butanamide with the appropriate reagents, is described. |
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| Keywords: | N-(pyrimid-2-yl)butanamide imidazo[1 2-a]pyrimidine pyrazole pyrazolo[3 4-b]pyridine pyrazolo[5 1-c][1 2 4]triazine] pyridazine pyridinethione |
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