Far-Red Dibenzo[a,j]Perylene-8,16-Dione Dyes as Fluorescent Enzyme Substrates and Tags for Biomolecules |
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| Authors: | Leslie W Deady Andrew B Hughes Indumathy B Mahadevan Nurul H Quazi Leann M Tilley |
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| Institution: | 1. Departments of Chemistry , La Trobe University , Bundoora, Vic, 3083, Australia;2. Biochemistry , La Trobe University , Bundoora, Vic., 3083, Australia |
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| Abstract: | The synthesis of fluorescent 2,10-derivatives of the title chromophore are described. The substituents contain amino-reactive N-hydroxysuccinimde ester and thiol-reactive iodoacetamide groups for attachment to biomolecules. A phosphate derivative was also prepared as an enzyme substrate. |
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| Keywords: | Paal–Knorr reaction pyrroles solvent‐free conditions sulfamic acid |
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