Iodine-Catalyzed Synthesis of 12-Aryl-8,9,10,12-tetrahydro-benzo[a]xanthen-11-one Derivatives via Multicomponent Reaction |
| |
| Authors: | Rui-Zhi Wang Li-Feng Zhang Zhen-Shui Cui |
| |
| Affiliation: | 1. College of Chemistry and Material Science , Hebei Normal University , Shijiazhuang, China orgsynchem@gmail.com;3. Department of Chemical and Environmental Engineering , Hebei Chemical and Pharmaceutical Vocational Technology College , Shijiazhuang, China;4. College of Chemistry and Material Science , Hebei Normal University , Shijiazhuang, China |
| |
| Abstract: | Iodine efficiently catalyzes the one-pot, three-component reaction of aryl aldehyde, 2-naphthol, and cyclic 1,3-dicarbonyl compound under solvent-free conventional heating conditions to afford the corresponding 12-aryl-8,9,10,12-tetrahydro-benzo[a]xanthen-11-one derivatives. The present approach offers several advantages such as shorter reaction times, good yields, low cost, and mild reaction conditions. |
| |
| Keywords: | Aldehyde iodine multicomponent reaction roman" >β-naphthol solvent-free conditions xanthene |
|
|
