Selective Bromination of Dehydroacetic Acid with N-Bromosuccinimide |
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| Authors: | Ajay Kumar Poonam Lohan |
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| Institution: | 1. Institute of Pharmaceutical Sciences , Kurukshetra University , Kurukshetra , India;2. Department of Chemistry , Kurukshetra University , Kurukshetra , India |
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| Abstract: | Bromination of dehydroacetic acid has been carried out with N-bromosuccinimide under various conditions. The reactions led to selective bromination, thereby offering efficient synthesis of 3β-bromodehydroacetic acid (3), 3β,5-dibromodehydroacetic acid (4), 3β,3β-dibromodehydroacetic acid (5), and 3β,3β,5-tribromodehydroacetic acid (6). |
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| Keywords: | 3-Acetyl-4-hydroxy-6-methyl-2H-pyran-2-one α-bromo ketones" target="_blank">α-bromo ketones dehydroacetic acid α" target="_blank">α α-dibromoketones" target="_blank">α-dibromoketones microwave irradiation N-bromosuccinimide |
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