One-Pot Synthesis and X-Ray Structure of New,Stable Tetrahydropyrrolo [1,2-a][1,10]phenanthrolines with Four Diastereoisomeric Centers |
| |
| Authors: | Reza Heydari Batool Tahamipour Niloofar Akbarzadeh Torbati Claudia Graiff Morteza Ziyaadini |
| |
| Affiliation: | 1. Department of Chemistry , University of Sistan and Baluchestan , Zahedan , Iran heydari@chem.usb.ac.ir;3. Department of Chemistry , Science and Research Branch, Islamic Azad University , Sirjan , Iran;4. Department of Chemistry , University of Sistan and Baluchestan , Zahedan , Iran;5. Dipartimento di Chimica Generale ed Inorganica , Chimica Analitica, Chimica Fisica, Universita di Parma , Parma , Italy |
| |
| Abstract: | ![]()
1,10-Phenanthrolinium N-ylides react with ethyl cyanoacetate and aromatic aldehydes via a domino-Knoevenagel cyclization to produce a new class of tetrahydropyrrolo [1,2-a][1,10] phenanthrolines with four diastereoisomeric centers as stable helical compounds in a simple, mild, and efficient protocol in excellent yields. Explicit structural elucidation of compounds was accomplished by single-crystal x-ray diffraction. |
| |
| Keywords: | Diastereoisomeric centers domino-Knoevenagel condensation 1,10-phenanthrolinium N-ylide tetrahydropyrrolo[1,2-a][1,10]phenanthrolines |
|
|
