Efficient One-Pot Synthesis of 2,2-Dimethyl-2H-chromenes via Pd(II)-Catalyzed Coupling and SiO2-Promoted Condensation of o-Halophenols with 2-Methyl-3-buten-2-ol |
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| Authors: | Jia Ti Tee Marzieh Yaeghoobi Noorsaadah Abd. Rahman |
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| Affiliation: | Department of Chemistry, University of Malaya, Kuala Lumpur, Malaysia |
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| Abstract: | An efficient synthesis of 2,2-dimethyl-2H-chromenes was accomplished by Pd(II)-catalyzed coupling and SiO2-promoted condensation of o-halophenols with 2-methyl-3-buten-2-ol (1,1-dimethylallyl alcohol) in one pot. The method is very general and can be useful for the synthesis of some natural 2,2-dimethyl-2H-chromenes. |
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| Keywords: | 2,2-Dimethyl-2H-chromene 2-methyl-3-buten-2-ol palladium phenol |
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