Synthesis of C 2-Symmetric Chiral Amino Alcohols: Their Usage as Organocatalysts for Enantioselective Opening of Epoxide Ring |
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| Authors: | Yilmaz Turgut Tarik Aral Mehmet Karakaplan Pinar Deniz Halil Hosgoren |
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| Institution: | 1. Faculty of Science, Department of Chemistry , University of Dicle , Diyarbakir, Turkey yturgut@dicle.edu.tr;3. Faculty of Science, Department of Chemistry , University of Dicle , Diyarbakir, Turkey |
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| Abstract: | A series of β-amino alcohols derivatives were synthesized from (R)-2-amino-1-butanol and (S)-1,2-propanediol, and they have been used as organocatalaysts in the racemic ring opening of epoxide in good yields with high enantiomeric excess (up to 97%). |
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| Keywords: | Asymmetric ring opening chiral amino alcohol epoxide organo catalysis |
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