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Novel Approach for the Synthesis of N-Substituted-4-(2-methyl-4-oxo-4H-quinazolin-3-yl)-butyramides |
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| Authors: | Mohammad Amir Israr Ali |
| Affiliation: | 1. Faculty of Pharmacy, Department of Pharmaceutical Chemistry , Hamdard University , New Delhi , India mamir_s2003@yahoo.co.in;3. Faculty of Pharmacy, Department of Pharmaceutical Chemistry , Hamdard University , New Delhi , India |
| Abstract: | A simple and convenient method for the synthesis of N-substituted-4-(2-methyl-4-oxo-4H-quinazolin-3-yl)-butyramides has been reported. Several aromatic and aliphatic amide derivatives of 4-(2-methyl-4-oxo-4H-quinazolin-3-yl)-butyric acid were prepared in 60–81% yields by refluxing it with different phosphazo compounds in toluene for approximately 1 h. |
| Keywords: | roman" >γ-Amino butyric acid butyramides phosphazo compounds quinazolin-4-one |