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Efficient Synthesis of Olmesartan Medoxomil,an Antihypertensive Drug |
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| Authors: | Karrothu Srihari Babu Mallepalli Srinivasa Reddy Amirisetty Ravindranath Tagore Gade Srinivas Reddy Sony Sebastian Mudunuru Satish Varma |
| Affiliation: | Center of Excellence , Dr. Reddy's Laboratories Ltd. , Bachupalli, Qutubullapur, India |
| Abstract: | This document describes a simple and robust process for the synthesis of olmesartan medoxomil. This tailored process allows us to synthesize olmesartan medoxomil on a large scale with 50% overall yield. Also, our process has excellent control of the impurity profile in all the stages. |
| Keywords: | Angiotensin receptor antagonist anti-hypertensive olmesartan |