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Efficient and Practical Synthesis of Dissymmetrical Ethers of 4-Nitrocatechol
Authors:Murugan Subashini  Kalpattu K. Balasubramanian
Affiliation:Shasun Research Centre , Chennai, India
Abstract:An efficient and practical synthesis of dissymmetrical ethers of 4-nitrocatechol from 5-nitrosalicyladehyde and 2-hydroxy-5-nitroacetophenone via Baeyer–Villiger oxidation is described. These dissymmetrical ethers are useful in the synthesis of various coccidiostats and other important pharmaceutical intermediates.
Keywords:Baeyer–Villiger oxidation  coccidiostats  2-hydroxy-5-nitroacetophenone  4-nitrocatechol  5-nitrosalicyladehyde
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