Convenient,Mild Catalytic Deprotection of Oximes to Carbonyl Compounds with Hydrogen Peroxide and Iodine Catalyst in Aqueous Acetonitrile |
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| Authors: | Nemai C Ganguly Subhasis Nayek Sujoy Kumar Barik |
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| Institution: | 1. Department of Chemistry , University of Kalyani , Kalyani, India nemai_g@yahoo.co.in;3. Department of Chemistry , University of Kalyani , Kalyani, India |
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| Abstract: | A clean, mild, and efficient catalytic deoximation procedure compatible with several common functional groups has been developed using 30% hydrogen peroxide activated by iodine catalyst in aqueous acetonitrile under essentially neutral conditions. The mechanistic features of an iodonium ion–driven nucleophilic cleavage of oximic Cdbnd]N have been revealed. |
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| Keywords: | Aldehyde 30% hydrogen peroxide iodine ketone oxime |
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