Nickel-Catalyzed Alkynylation of Aryl Iodides (Sonogashira Reaction) in Water |
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| Authors: | Mohammad Bakherad Ali Keivanloo Samira Mihanparast |
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| Institution: | 1. Faculty of Chemistry , Shahrood University of Technology , Shahrood , Iran m.bakherad@yahoo.com;3. Faculty of Chemistry , Shahrood University of Technology , Shahrood , Iran |
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| Abstract: | The Sonogashira coupling of terminal acetylenes with aryl iodides, catalyzed by Ni-Cu, in the presence of sodium lauryl sulfate as the surfactant and cesium carbonate as the base, in water, leads to the formation of aryl alkyne products. |
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| Keywords: | Alkynylation aryl iodide nickel catalyst Sonogashira reaction |
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