Synthesis of New 2-Aryl Substituted 2,3-Dihydroquinazoline-4(1H)-ones Under Solvent-Free Conditions,Using Molecular Iodine as a Mild and Efficient Catalyst |
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| Authors: | Shahnaz Rostamizadeh Ali Mohammad Amani Reza Aryan Hamid Reza Ghaieni Nasrin Shadjou |
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| Institution: | 1. Department of Chemistry, Faculty of Sciences , K. N. Toosi University of Technology , Tehran, Iran shrostamizadeh@yahoo.com;3. Department of Chemistry, Faculty of Sciences , K. N. Toosi University of Technology , Tehran, Iran |
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| Abstract: | A simple, inexpensive, and efficient one-pot synthesis of 2,3-dihydroquinazoline-4(1H)-one derivatives under solvent-free conditions using a catalytic amount of iodine with excellent product yields is reported. This methodology provides easy, quantitative access to various 2,3-dihydroquinazoline-4(1H)-one derivatives, using commercially available iodine as a catalyst. |
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| Keywords: | 2 3-Dihydroquinazolinone heterocycles molecular iodine multicomponent reactions solvent-free condition |
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