Synthesis,Reactions, and Antimicrobial Evaluation of Some Polycondensed Thienopyrimidine Derivatives |
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| Authors: | Aymn E Rashad Ahmed H Shamroukh Randa E Abdel-Megeid Wael A El-Sayed |
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| Institution: | 1. Photochemistry Department , National Research Centre , Dokki, Cairo, Egypt aymnelzeny@yahoo.com;3. Photochemistry Department , National Research Centre , Dokki, Cairo, Egypt |
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| Abstract: | Some novel indeno2,1-b]thiophenes, indeno1′,2′:4,5]thieno2,3-d]1,2,3]triazines, indeno1′,2′:4,5]thieno2,3-d]pyrimidines, indeno1′,2′:4,5]thieno2,3-d]1,3]thiazolo3,2-a]pyrimidines, and indeno1′,2′:4,5]thieno2,3-d]1,2,4]triazolo4,3-a]pyrimidines 2–16 were prepared starting with 2-aminoindeno2,1-b]thiophene-3-carboxylic acid amide ( 1 ). Furthermore, the antimicrobial evaluation of the prepared products showed that many of them revealed promising antimicrobial activity. |
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| Keywords: | Antimicrobial evaluation indeno[2 1-b]thiophenes indenothienopyrimidines thiazolothienopyrimidines thienotriazolopyrimidines |
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