Efficient Synthesis of Aryl Hydroxylactams by Reducing Imides With Activated Zinc Dust |
| |
| Authors: | Xiu‐hua Yuan Min‐jie Zhang Chuan‐qing Kang Hai‐quan Guo Xue‐peng Qiu |
| |
| Institution: | State Key Laboratory of Polymer Physics and Chemistry , Changchun Institute of Applied Chemistry, Graduate School of Chinese Academy of Sciences , Changchun, China Phone: 086‐0431‐5262203 Fax: 086‐0431‐5262203 |
| |
| Abstract: | A series of aryl hydroxylactams (2a, 2b, 2d–2g, 2i–2k, 2m, and 2n) was synthesized by partially reducing aryl cyclic imides in moderate to excellent yields with activated zinc dust alone in acetic acid. This method was regiospecific and can be employed as an alternative for reported methods to partially reduce aryl cyclic imides. |
| |
| Keywords: | Hydroxylactams regiospecific synthesis zinc dust |
|
|
