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Caro's Acid–Silica Gel: An Efficient and Versatile Catalyst for the One-Pot Synthesis of Tetrahydrobenzo[b]pyran Derivatives
Authors:Hossein Abdi Oskooie  Narges Karimi  Mojgan Ebrahim Zadeh
Institution:Department of Chemistry , School of Science, Azzahra University , Vanak, Tehran, Iran
Abstract:An efficient one-pot synthesis of tetrahydrobenzob]pyran is described. This involved the three-component reaction of aromatic aldehydes, molononitrile, and dimedone in the presence of a catalytic amount of Caro's acid supported on silica gel in ethanol/water under reflux.
Keywords:Aldehydes  dimedone  malononitrile  multicomponent reaction  tetrahydrobenzo[b]pyran
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