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Facile Synthesis of Trisubstituted Thioindoles via a Novel Tricyclic Thiolactone Intermediate |
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| Authors: | Cangming Yang Ronald M. Kim Emma R. Parmee Qiang Tan |
| Affiliation: | 1. Department of Basic Chemistry , Merck Research Laboratories , Rahway, New Jersey, USA cangming_yang@merck.com;3. Department of Basic Chemistry , Merck Research Laboratories , Rahway, New Jersey, USA |
| Abstract: | Methodology to conveniently and systematically prepare biologically active indole 9 is described. |
| Keywords: | Alkylation demethylation substituted indole thiolactone |