Mild and Efficient Synthesis of Benzo-Fused Seven- and Eight-membered Ring Lactams: A Convenient Approach to Biologically Interesting Chemotypes |
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| Authors: | Jayne L. Kenwright Warren R. J. D. Galloway Lars Wortmann |
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| Affiliation: | 1. Department of Chemistry , University of Cambridge , Cambridge , United Kingdom;2. Bayer Schering Pharma AG , Berlin , Germany |
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| Abstract: | A general and efficient method for the synthesis of benzo-fused 7- and 8-membered ring lactams via the Beckmann rearrangement of cyclic oximes is presented. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications® to view the free supplemental file. |
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| Keywords: | Lactam medium ring methodology |
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