Preparation and Characterization of Some Substituted Benzyl N-Nitrosocarbamates Containing an N-2-(Methylthio)ethyl or a Bis(2-aminoethyl)sulfide Functionality |
| |
Authors: | Satya Venkata Eric Shamo |
| |
Institution: | Department of Chemistry, University of Dayton , Dayton, Ohio, USA |
| |
Abstract: | The synthesis and characterization of some substituted benzyl N-nitrosocarbamates with an N-2-(methylthio)ethyl or a bis(2-aminoethyl)sulfide functionality is reported, as a part of a long-term goal to design and prepare novel photolabile structures that could be used as substances for controlled release of alkylating and/or crosslinking agents. The synthesis was accomplished by reaction of benzyl chloroformates with the corresponding amines, resulting in the preparation of carbamates. The latter were subsequently nitrosated, utilizing two different N-nitrosation methods, to yield the target structures. |
| |
Keywords: | Carbamates 2-(methylthio)ethyl group N-nitrosation N-nitrosocarbamates |
|
|