Sonochemical Formation of Iodohydrin and Epoxide from Cyclohexene |
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| Authors: | Vanessa S Fernandes Antônio Aarão Serra |
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| Institution: | Department of Chemical Engineering, Fine Chemistry Laboratory, Faculdade de Engenharia Química de Lorena, Faenquil , Lorena, Brazil |
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| Abstract: | Ultrasonic irradiation substantially improves the reaction of cyclohexene with I2 in aqueous dioxane in the presence of Cu(OAc)2 · H2O to generate the expected iodohydrin in high yield. The product undergoes cyclization to the epoxide by biphasic treatment with either Na2CO3 or KOH in a sonication‐sensitive step. |
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| Keywords: | Epoxidation iodohydrin ultrasonic irradiation |
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