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The Effect of the Nature and Structure of Adsorbents on Interaction with Ibuprofen
Authors:Gun'ko  V M  Mikhalovskii  S V  Melillo  M  Voronin  E F  Nosach  L V  Pakhlov  E M
Institution:(1) Institute of Surface Chemistry, National Academy of Sciences of Ukraine, 17 Generala Naumova Vul., 03164 Kyiv, Ukraine;(2) University of Brighton, Lewes Road, Brighton, BN2 4GJ, UK
Abstract:The interaction of ibuprofen 2-(4-isobutylphenyl)propionic acid] with the surface of carbon and oxide adsorbents was investigated. The significant role of wide pores during the adsorption of ibuprofen on carbon adsorbents in the presence of protein molecules was demonstrated. At low concentrations ibuprofen is adsorbed on the surface of hydrophilic and hydrophobic adsorbents in the form of a monomer, but the contribution from the adsorbed dimer increases with increase in its concentration.
Keywords:adsorption  ibuprofen  BSA  activated carbon  highly dispersed silica
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