Mannich reaction in the series of 7-hydroxy-3-phenoxychromones and their derivatives |
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| Authors: | M. M. Garazd Ya. L. Garazd A. S. Ogorodniichuk V. V. Shilin A. V. Turov V. P. Khilya |
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| Affiliation: | (1) Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of the Ukraine, ul. Murmanskaya, 1, 253660 Kiev;(2) Kiev Taras Shevchenko University, ul. Vladimirskaya, 64, 252033 Kiev |
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| Abstract: | The Mannich condensation of amino acids with 3-phenoxychromones and polyhydroxy-α-phenoxyacetophenones has given a series of 8-carboxyalkylaminomethylchromones and 3-carboxymethylaminomethyl-2,4-dihydroxy-α-phenoxyacetophenones. Some features of the course of the Mannich reaction as a function of the structures of the chromones and acetophenones have been studied. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 475–481, July–August, 1998. |
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