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Convenient one-step synthesis of 5-carboxy-seminaphthofluoresceins |
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| Authors: | Peter Hammershøj Erling Thyrhaug Pernille Harris Pramod K Ek Thomas L Andresen Mads H Clausen |
| Institution: | 1. Department of Chemistry, Technical University of Denmark, Building 207, 2800 Kgs. Lyngby, Denmark;2. Center for Nanomedicine and Theranostics, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark;3. Department of Chemical Physics, Lund University, Getingevägen 60, 22241 Lund, Sweden;4. Department of Micro- and Nanotechnology, DTU Nanotech, Technical University of Denmark, Building 423, 2800 Kgs. Lyngby, Denmark |
| Abstract: | The one-step synthesis and characterization of a series of regioisomerically pure 5-carboxy-seminaphthofluoresceins (5-carboxy-SNAFLs) is reported. The optical properties were determined in aqueous buffer at around biological pH, and highly pH sensitive, large Stokes-shift fluorophores with emission in the deep-red to near-infrared region were identified. |
| Keywords: | 5-Carboxy-seminaphthofluoresceins Near-infrared-emitter One-step synthesis Enhanced Stokes shifts |
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