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Solvent-Free Mechanochemical Synthesis of Aryl Glycosides[ 1 ]
Authors:Premanand Ramrao Patil  K. P. Ravindranathan Kartha
Affiliation:Department of Medicinal Chemistry , National Institute of Pharmaceutical Education and Research , S.A.S. Nagar, Punjab, 160 062, India
Abstract:
Aryl glycosides have been prepared from a range of readily available glycosyl halides by a solvent-free mechanochemical procedure employing a planetary ball mill in excellent yields. Besides being a solvent-free reaction, the procedure has been successful in eliminating the need for employing any phase-transfer catalyst in the reaction.
Keywords:Aryl glycoside synthesis  Mechanochemical reactions  Chemistry by ball milling  Solvent-free synthesis
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