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Development of a dedicated isotope mass spectrometer for the noninvasive diagnostics of humans infected with Helicobacter Pylori |
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| Authors: | N M Blashenkov E S Sheshenya S M Solov’ev L N Gall’ V M Sachenko I V Zarutskii N R Gall’ |
| Institution: | 1. Ioffe Physical Technical Institute, Russian Academy of Sciences, Politekhnicheskaya ul. 26, St. Petersburg, 194021, Russia 2. St. Petersburg State Polytechnical University, Polytechnicheskaya ul. 29, St. Petersburg, 195251, Russia 3. Institute for Analytical Instrumentation, Russian Academy of Sciences, Rizhskii pr. 26, St. Petersburg, 190103, Russia 4. ELMITEK Gmbh, Velbert, Germany 5. OOO Teknnan, Zheleznovodskaya ul. 17/5, St. Petersburg, 199155, Russia |
| Abstract: | A dedicated isotope mass spectrometer for the noninvasive diagnostics of humans infected with Helicobacter Pylori using the isotope respiratory test is developed. A low-aberration mass analyzer is calculated, an input system that makes it possible to eliminate the memory effects is developed, and a small-size ion detector is constructed. The mass spectrometer is created, and the tests are performed. The measurement accuracy of the 13C/12C and 16O/18O isotope ratios are 1.7 and 2.2‰, respectively. Preliminary medical tests show that the spectrometer can be employed for the desired diagnostics. |
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