Synthesis,spectral studies,and catalytic and antibacterial activity of Ru(II) complexes with coordinated amides

Twelve Ru(II) complexes with coordinated amides were synthesized and characterized by elemental, IR, ¹H, ¹³C, ³¹P NMR, mass, and electronic spectral analysis, along with magnetic and conductance measurements. Molecular formulas and octahedral structures have been tentatively proposed. These complexes were used as catalysts for the hydrolysis of rivastigmine and neostigmine. The hydrolyzed products were coupled with 3-methyl benzothiazolinone hydrazone reagent in the presence of sodium metaperiodate and the resulting colored products were determined spectrophotometrically. The yields of hydrolyzed products were found to be 98.47% and 99.75% respectively. All the ligands and Ru(II) complexes were screened for antibacterial activity. Published in Zhurnal Prikladnoi Spektroskopii, Vol. 75, No. 6, pp. 867–874, November–December, 2008.