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The Synthesis and Characterization of the Poly[N-vinylpyrrolidone-co-ethylidene-bis-3-(N-vinyl-2-pyrrolidone)] Hydrogel Matrix for Drug Delivery to the Gastrointestinal Tract
Authors:Jakub Hrib  Jakub Sirc  Radka Hobzova  Eva Krumbholcova  Ales Zak  Barbora Stankova  Ondrej Slanar  Robert Hromadka  Jiri Michalek
Institution:1. Institute of Macromolecular Chemistry AS CR, Heyrovsky Sq. 2, 162 06 Prague 6, Prague, Czech Republic;2. Fourth Department of Medicine, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic;3. Institute of Pharmacology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic;4. Research and Development Center, C2P Ltd., Chlumec nad Cidlinou, Czech Republic
Abstract:
Keywords:controlled drug release  disintegration/swelling test  gastrointestinal tract  hydrogel  nicotinic acid  poly(N-vinylpyrrolidone)
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