| 富勒醇清除OH自由基的ESR研究 |
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| 引用本文： | 祝严师,孙大勇.富勒醇清除OH自由基的ESR研究[J].高等学校化学学报,1996,17(7):1127-1129. |
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| 作者姓名： | 祝严师 孙大勇 |
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| 作者单位： | 中国科学院长春应用化学研究所应用谱学开放实验室 |
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| 基金项目： | 中国科学院应用谱学开放实验室和延边敖东药业集团公司资助 |
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| 摘 要： | 富勒醇清除·ＯＨ自由基的ＥＳＲ研究祝严师，孙大勇，刘桂珍，刘子阳，詹瑞云，刘淑莹（中国科学院长春应用化学研究所应用谱学开放实验室，长春，１３００２２）关键词Ｃ_（６０），富勒醇，ＯＨ自由基，自旋捕捉，ＥＳＲ生物体内的许多现象均涉及到自由基反应，现已发?..
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| 关 键 词： | 富勒醇 OH自由基 自旋捕捉 ESR 碳60 |
An ESR Study on OH-radical Scavenging Activity of Water-soluble Fullerenols |
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| ZHU Yan-Shi,SUN Da-Yong,LIU Gui-Zhen,LIU Zi-Yang,ZHAN Rui-Yun,LIU Shu-Ying.An ESR Study on OH-radical Scavenging Activity of Water-soluble Fullerenols[J].Chemical Research In Chinese Universities,1996,17(7):1127-1129. |
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| Authors: | ZHU Yan-Shi SUN Da-Yong LIU Gui-Zhen LIU Zi-Yang ZHAN Rui-Yun LIU Shu-Ying |
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| Abstract: | Water-soluble polyhydroxylated fullerene derivatives(fullerenol) were synthesized,and their scavenging ability for OH-radical was studied by the combination of ESR spectroscopy and spin-trapping technique with phenyl-t-butyl-nitrone. It was found that fullerenols showed an excellent efficiency in eliminating OH free radicals generated by UV photolysis of H2O2.At an applied fullerenol concentration of 0.3mg/mL in the final solution,a radical scavenging efficiency of approximate 95%was achieved, revealing the potential use of these compounds as novel potent free radical scavengers in biological systems. |
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| Keywords: | C60 Fullerenol OH-radical Spin-trapping ESR |
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