Total synthesis of amaryllidaceae alkaloid buflavine |
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| Authors: | Hoarau Christophe Couture Axel Deniau Eric Grandclaudon Pierre |
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| Affiliation: | Laboratoire de Chimie Organique Physique, UPRESA 8009, Université des Sciences et Technologies de Lille, Batiment C3, DUSVA, 59655 Villeneuve d'Ascq Cedex, France. |
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| Abstract: | A concise synthesis of the amaryllidaceae alkaloid buflavine (1) and its regioisomer (2) involving sequential Meyers' biaryl coupling, enecarbamate formation, and hydrogenation followed by ultimate intramolecular reductive amination is presented. |
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