Synthèse de dérivés O-substitués du (dihydroxy-3′,4′ phényl)-2 indole par utilisation de groupes protecteurs sulfonylés

O-Substituted derivatives of 2-(3,4-dihydroxyphenyl)indole have been synthesized from acetovanillone by various methods using hydroxyl protective groups such as benzene sulfonyl and methylsulfonyl. Thus these groups facilitate Fischer and Bischler indole synthesis. Moreover, selective O-demethylation and O-alkylation reactions are allowed. Finally, the already quoted protective groups may be easily removed to yield back the 2-(4-hydroxy-3-alkyloxyphenyl)indoles.