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Imaging cytoplasmic cAMP in mouse brainstem neurons
Authors:SL Mironov  E Skorova  G Taschenberger  N Hartelt  VO Nikolaev  MJ Lohse  S Kügler
Affiliation:1. DFG-Center of Molecular Physiology of the Brain, Department of Neuro- and Sensory Physiology, Georg-August-University, Humboldtallee 23, 37073, G?ttingen, Germany
2. Department of Neurology, University Medical Center G?ttingen, Waldweg 33, 37073, G?ttingen, Germany
3. Institute of Pharmacology and Toxicology, University of Würzburg, Versbacher Str. 9, 97078, Würzburg, Germany
Abstract:

Background  

cAMP is an ubiquitous second messenger mediating various neuronal functions, often as a consequence of increased intracellular Ca2+ levels. While imaging of calcium is commonly used in neuroscience applications, probing for cAMP levels has not yet been performed in living vertebrate neuronal tissue before.
Keywords:
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