One-pot synthesis of functionalized thioureas by reaction of benzoyl isothiocyanates, secondary amines, and alkyl propiolates |
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Authors: | Issa Yavari S. Zahra Sayyed-Alangi Maryam Sabbaghan Rahimeh Hajinasiri Nasir Iravani |
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Affiliation: | (1) Chemistry Department, Science and Research Campus, Islamic Azad University, Ponak, Tehran, Iran;(2) Chemistry Department, Tarbiat Modares University, Tehran, Iran |
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Abstract: | An efficient one-pot synthesis of functionalized thioureas is described via three-component reaction of benzoyl isothiocyanates, secondary amines, and alkyl propiolates in the presence of triphenylphosphine (20 mol%). Correspondence: Issa Yavari, Chemistry Department, Tarbiat Modares University, PO Box 14115-175, Tehran, Iran |
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Keywords: | Benzoyl isothiocyanate Activated acetylenes Secondary amines Triphenylphosphine Three-component reaction. |
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