| 温度及pH值敏感水凝胶的合成和应用 |
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| 引用本文： | 黄月文,罗宣干,卓仁禧.温度及pH值敏感水凝胶的合成和应用[J].广州化学,1996(2). |
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| 作者姓名： | 黄月文 罗宣干 卓仁禧 |
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| 作者单位： | 中国科学院广州化学研究所!广州(黄月文)，武汉大学化学系!武汉(罗宣干，卓仁禧) |
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| 摘 要： | 直接将丙烯酸单体与N-异丙基丙烯酸胺共聚交联合成了温度及pH值敏感的水凝胶。包埋于水凝胶中的药物的释放随温度升高和pH值增大而加快，药物的释放兼有温度和pH值敏感性，对pH值的响应更加显著。
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| 关 键 词： | 温度及pH值敏感 水凝胶 控制释放 |
The Preparation and Application of the Temperature and pH-sensitive Hydrogels |
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| Huang Yuewen.The Preparation and Application of the Temperature and pH-sensitive Hydrogels[J].Guangzhou Chemistry,1996(2). |
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| Authors: | Huang Yuewen |
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| Abstract: | Directly copolyffierization and cross-linking between acrylic acid and N-isopropylacrylamide, the preparation of temperature & pH-sensitive hydrogels was performed.The release of drug loaded in these hydrogels was quickened by the elevation of temperature and rising of pH, and responseti more distinctly to the latter. |
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| Keywords: | temperature & pH-sensitive hydrogel controlled release |
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