Chemical and ecotoxicological assessment of poly(amidoamine) dendrimers in the aquatic environment |
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Authors: | I.J. SuarezR. Rosal,A. RodriguezA. Ucles,A.R. Fernandez-Alba,M.D. HernandoE. Garcí a-Calvo |
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Affiliation: | a Department of Chemical Engineering, University of Alcalá, 28771 Alcalá de Henares, Spain b Centro de Investigaciones de la Energía Solar (CIESOL), Department of Hydrogeology and Analytical Chemistry, University of Almería, 04120 La Cañada de San Urbano, Almería, Spain c National Reference Centre for Persistent Organic Pollutants, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain d Fundación IMDEA-Agua, C/ Punto Net 4, 2a planta, Edificio ZYE, Parque Científico Tecnológico de la Universidad de Alcalá. 28805, Alcalá de Henares, Madrid, Spain |
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Abstract: | Poly(amidoamine) (PAMAM) dendrimers are attracting great interest as a consequence of their unique properties as carriers of active molecules in aqueous media, as we expect their presence in the environment to be widespread in the future.In this article, we focus on the analytical methods to characterize and to determine these polymeric materials in waters and on their ecotoxicity for aquatic organisms. We review physical characterization techniques (e.g., light scattering, electron microscopy, atomic force microscopy) and analytical techniques, mainly based on liquid chromatography, so as to consider their main capabilities, advantages and drawbacks. We assessed the toxicity of certain PAMAM dendrimers for the green alga Pseudokirchneriella subcapitata by determining the EC50 and correlating it with the ζ-potential. |
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Keywords: | Aqueous environment Atomic force microscopy Dendrimer Ecotoxicity EC50 Electron microscopy Light scattering Liquid chromatography Poly(amidoamine) ζ-potential |
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