Preparation of isoprostanes and neuroprostanes |
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| Authors: | Quan Long Guo Cha Jin Kun |
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| Institution: | Department of Chemistry, University of Alabama, Tuscaloosa, Alabama 35487, USA. |
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| Abstract: | A new approach to isoprostanes and neuroprostanes featuring cis-dialkyl stereochemistry at the cyclopentane ring has been developed by employing an intramolecular cross-coupling reaction of an alkyl iodide and a tethered alkenylsiloxane for stereoselective installation of a functionalized omega-side chain. |
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