RETRACTED ARTICLE: Microenvironment characterization for a novel biocompatible hybrid carbon-silicon material |
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Authors: | XiHua Sui QingFang Zha MingBo Wu YanSheng Guo |
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Institution: | (1) State Key Laboratory of Heavy Oil, China University of Petroleum, Dongying, 257061, China |
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Abstract: | The compatible carbon-silicon complex materials originated from precursor diglycerylsilane (DGS) and sugar-modified silane
N-(3-triethoxysilylpropyl)gluconamide (GLS) have gained substantial popularity by demonstrating admirable properties to stabilize
entrapped biomolecules. The microenvironment inside these materials, especially the distribution of sugar moieties inside
the matrix, which is likely the most critical factor determining compatibility of these materials, still remains unclear.
To deeply investigate the biocompatibility mechanism of these materials, we have adopted two different preparation routes
for these materials by introducing GLS into the starting DGS sol stage, but things are different after the DGS gel is formed.
A fluorescence probe rhodamine 6G is introduced herein in the DGS sol to monitor the distribution of GLS moieties, as well
as the evolution of the microenvironment inside resulting materials. All in all, the findings demonstrated that the timing
of GLS addition plays a critical role in controlling the evolution of the inner structure of materials, suggesting that this
factor provides a promising route to tune the properties of the resulting materials.
Supported by the National Natural Science Foundation of China (Grant No. 20876176), Scientific Research Foundation for the
Returned Overseas Chinese Scholars by the State Education Ministry, Key Project of Chinese Ministry of Education (Grant No.
109100), Doctoral Project of Shandong Province (Grant No. 2008BS09013), Research Foundation of Key Laboratory of Carbon Materials,
Institute of Coal Chemistry, CAS (Grant No. KFJJ0506), and Natural Science Foundation of Shandong Province (Grant No. Q2007B02) |
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Keywords: | biocompatibility carbon-silicon complex microenvironment characterization |
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