A new synthesis of highly functionalized 2H-pyran derivatives |
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| Authors: | Issa Yavari Mohammad Bayat |
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| Institution: | Department of Chemistry, University of Tarbiat Modarres, P.O. Box 14115-175, Tehran, Iran |
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| Abstract: | Ethyl oxo-(2-oxo-cycloalkyl)-ethanoates undergo a smooth reaction with triphenylphosphine and dialkyl acetylenedicarboxylates via intramolecular Wittig reaction to produce spiro-cyclobutene derivatives. These spiro systems undergo electrocyclic ring opening reaction to produce electron-deficient 1,3-dienes, which spontaneously cyclize to 2H-pyran derivatives. |
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| Keywords: | cyclobutene spiro systems 2H-pyran CH-acid intramolecular Wittig reaction acetylenic esters |
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