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Toward a practical and waste-free synthesis of thioureas in water
Authors:Najmedin Azizi  Alireza Khajeh-Amiri  Hossein Ghafuri  Mohammad Bolourtchian
Affiliation:(1) Research and Technology, Chemistry and Chemical Engineering Research Center of Iran, P.O. Box 14335-186, Tehran, Iran
Abstract:An operationally simple and entirely green protocol for the synthesis of thiourea derivatives by the reaction of carbon disulfide with primary amines in pure water is developed. This reaction is a highly atom-economic process for production of highly pure, hindered thioureas without any catalyst and tedious work-up.
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