Toward a practical and waste-free synthesis of thioureas in water |
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Authors: | Najmedin Azizi Alireza Khajeh-Amiri Hossein Ghafuri Mohammad Bolourtchian |
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Affiliation: | (1) Research and Technology, Chemistry and Chemical Engineering Research Center of Iran, P.O. Box 14335-186, Tehran, Iran |
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Abstract: | An operationally simple and entirely green protocol for the synthesis of thiourea derivatives by the reaction of carbon disulfide with primary amines in pure water is developed. This reaction is a highly atom-economic process for production of highly pure, hindered thioureas without any catalyst and tedious work-up. |
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