Green chemistry approaches to the regioselective synthesis of spiro heterobicyclic rings using iodine as a new and efficient catalyst under solvent-free conditions |
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Authors: | Dipak Prajapati Debajyoti Bhuyan Mukut Gohain and Wenhao Hu |
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Institution: | (1) Institut des Sciences Mol?culaires de Marseille, UMR CNRS 6263 iSm2, Aix-Marseille Universit? – Centre Saint J?r?me, Service 531, 13397 Marseille Cedex 20, France; |
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Abstract: | Abstract Iodine catalyzes the pseudo four-component reaction of an aldehyde, a urea or thiourea, and cyclic 1,3-dicarbonyl compounds
under microwave irradiation in a solvent-free condition to yield various σ symmetric spiro heterobicyclic rings in excellent yields. |
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